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Therefore, identifying neural substrates that mediate the rewarding effects of drugs of abuse will help in our understanding of processes involved in the development of drug addiction and help in the discovery of medications for its treatment. The increase in heroin self-administration was however observed in the first hour of a three hour self-administration session, thus suggesting that the increase in heroin self-administration may be an attempt to compensate for the decrease in the rewarding effects of heroin Xi and Stein, In contrast, drug rewards are consumed for their ability to produce pleasure and euphoria.

Anna mpeg nicole sex smith

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Anna mpeg nicole sex smith

Anna mpeg nicole sex smith

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  1. Drugs of abuse and alteration of glutamate transmission Drugs of abuse alter glutamate transmission via different mechanisms.

  2. In fact, drug-induced plasticity in glutamatergic transmission is critically involved in the development of drug addiction Kalivas, , ; van Huijstee and Mansvelder,